I thought Anne McCaffrey's Crystal Singer, aka Killashandra Ree was pretty feisty!

Morgaine, from the pen of C J Cherryh. Armour, sword; check. Has not yet, to my knowledge, done the marriage and babies thing.

Xena. However a big tick for 'Fights like a ninja'.

Aeyrn Sun, Chiana, Zhaan and the living ship Moya in 'Farscape'

River Tam [damaged waif fu], Kaylee [Greasy engineer who loves engines and sex], Zoe [stoic gun toting warrior woman], Inara [High caste Companion] from 'Firefly'.

Marvels Adventures of Shield : Skye [hacker extraordinaire], Melinda May [oriental stoic kick ass woman], Jemma Simmons [Science specialist].